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Framework for Rational Donor Selection in Fecal Microbiota Transplant Clinical Trials
Fecal Microbiota Transplant (FMT) is gaining traction as a potentially effect treatment of the increasing number of diseases that have been linked to microbiome dysbiosis.
Mapping Human Microbiome Drug Metabolism by Gut Bacteria and Their Genes
In a recent study published in Nature by Zimmerman (et.al), researchers begin to uncover how intestinal bacteria chemically modify prescription drugs.
Spotlight on Brittany Berdy, PhD
This month I interviewed Brittany Berdy, PhD, who is CMIT’s pinpoint person for their Bio-Microbial Library Strain Collection.
Progressive Shifts in the Gut Microbiome Reflect Prediabetes and Diabetes Development in a Treatment-Naive Mexican Cohort
To look for associations between the gut microbiome composition and development of Type 2 Diabetes, CMIT collaborated with researchers at institutes and hospitals within Mexico to study a cohort that had not been been diagnosed with, or treated for T2D, avoiding the potential influences of medication and lifestyle changes on gut microbes.
CMIT Annual Request for Applications is Open
The Center for Microbiome Informatics and Therapeutics was founded to accelerate the development of therapeutics to treat microbiome-associated disease, with a core focus on Inflammatory Bowel Disease (IBD).
Going for the Gut
Working to preserve human microbiome diversity
Multi-omics of the Gut Microbial Ecosystem in Inflammatory Bowel Diseases
In a recently published paper in Nature, Lloyd-Price (et.al) provide a comprehensive analysis of the longitudinal variation in the gut microbiome of patients with IBD.
Fecal Microbiota Transplant as Treatment of Hepatic Encephalopathy
CMIT is collaborating with Dr. Patricia Pringle and Dr. Raymond Chung from Massachusetts General Hospital (MGH) on a new study that is investigating the potential role of fecal microbiota transplantation (FMT) as a treatment for hepatic encephalopathy.
An Interview with Dr. Jessica R. Allegretti, MD, MPH
Dr. Jessica Allegretti is an inspiring example of a clinician who works passionately to improve the lives of those suffering from Inflammatory Bowel Disease (IBD).
A Library of Human Gut Bacterial Isolates Paired with Longitudinal Multiomics Data Enables Mechanistic Microbiome Research
The Broad Institute and OpenBiome Microbiome Library (BIO-ML) now supplies a comprehensive collection of nearly 8,000 intestinal bacterial isolates, paired with nearly 4,000 genome sequences, to serve as an open access investigational resource.