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Centenarians have a distinct microbiome that may help support longevity
Intestinal microbes in people aged 100 or over produce unique bile acids that might help keep infections at bay.
Manpower and manholes: Alm lab joins fight against Covid-19
When the Covid-19 pandemic was declared, both current and former members of the Alm lab jumped into action to help communities stay ahead of local case surges.
MIT Microbiome Club hosts 5th Annual Microbiome Symposium
Conferences and large scientific meetings energize the research community. Sharing new findings, making new connections, learning about new techniques, exposing trainees to the wider field—these interactions fuel innovation.
Xavier lab reveals how the body fights Covid-19
CMIT Co-Director Ramnik Xavier is one of many CMIT investigators leveraging their expertise and resources to study SARS-CoV-2, the virus that causes Covid-19. Pairing their expertise in immunology with that of computational and structural biologists, members of the Xavier lab reveal the reason why immune responses to Covid-19 vary so widely between individuals. By characterizing […]
How industrialized life remodels the microbiome
A new study from an MIT-led team has revealed that these bacterial populations can remake themselves within the lifetime of their host, by passing genes back and forth.
Turning microbiome research into a force for health
A diverse group of researchers is working to turn new discoveries about the trillions of microbes in the body into treatments for a range of diseases.
Spotlight on Dr. Majdi Osman, MD MPH
An interview with Dr.Majdi Osman, the clinical director of OpenBiome. We talk to Osman about what it’s like to manage the world’s largest stool bank, his ongoing pursuit to try and help children who suffer from malnourishment, and even his extracurricular activity: writing a children’s book!
Development of a Covalent Inhibitor of Gut Bacterial Bile Salt Hydrolases
To better understand the pathologic impact of intestinal bile acids on host health, CMIT faculty designed a non-toxic inhibitor that reduces secondary bile acid production in the intestine to better understand the impact of these metabolites.
Gut Microbiota Composition and Functional Changes in Inflammatory Bowel Disease and Irritable Bowel Syndrome
Authors unveil a large-scale metagenomic microbiome analysis from patients with both Inflammatory Bowel Disease and Irritable Bowel Syndrome.
Predictive Metabolomic Profiling of Microbial Communities Using Amplicon or Metagenomic Sequences
Researchers create a novel computer model that predicts the metabolic activity of new microbial communities using widely available metagenomic sequencing.