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Summary: Engineering Phage Host-Range and Suppressing Bacterial Resistance through Phage Tail Fiber Mutagenesis
Performing targeted mutagenesis of specific phage regions that are critical for bacterial recognition, creating diversity at binding regions that slows evolution of bacterial resistance mechanisms.
Summary: Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis
In a recent study, researchers use single cell sequencing of intestinal tissue biopsies from diseased and healthy patients to create a cell atlas that lends novel insight into the cellular pathways that link implicated genes to UC pathophysiology.
Spotlight on Dr. Duane Wesemann, MD, PhD
Interview with Dr. Duane Wesemann, an Assistant Professor at Harvard Medical School, and a Principal investigator in the Division of Rheumatology, Immunology and Allergy at the Brigham and Women’s Hospital.

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