Research

Our translational research platform unites leading researchers and clinicians across a variety of disciplines to develop improved methods of disease surveillance and treatment.

We want to support research and clinical trials that will help us learn how to engineer the microbiome to help patients and restore health. These efforts are supported by a strong foundation of resources: our Microbial Omics Core Facility, Data Analysis Pipeline, and the The Broad Institute-OpenBiome Microbiome Library.

Sponsored Project

The Broad Institute-OpenBiome Microbiome Library: A Foundation for a New Generation of Microbiome Therapeutics

Primary Researcher:
Eric Alm
Mathilde Poyet
Mathieu Groussin
Julian Avila Pacheco
Hera Vlamakis
Xiaofang Jiang
Sean Gibbons
Ramnik Xavier

Clinical Trial

Fecal Microbiota Transplant from a Rational Stool Donor Improves Hepatic Encephalopathy: A Randomized Clinical Trial

Primary Researcher:
Jasmohan Bajaj

Clinical Trial

Analysis of Gut Bacteria in Patients with Clostridium Difficile-Associated Diarrhea

Primary Researcher:
Laura Martello-Rooney

Clinical Trial

Role of Diet and Obesity in Shaping the Human Gut Microbiome

Primary Researcher:
Thomas Gurry

Clinical Trial

Characterizing the Relationship between HLA-B27, Axial Spondyloarthritis, Uveitis, and the Gut Microbiome

Clinical Trial

Evaluation of Gut Microbiome in Peanut-Allergic Patients Before and After Fecal Microbiota Transplantation

Primary Researcher:
Rima Rachid

Clinical Trial

Analysis of Samples from STOOL Study

Clinical Trial

Dietary Therapy for Crohn’s Disease and Ulcerative Colitis: A Pilot Study of Efficacy and Durability

Primary Researcher:
Ashwin Ananthakrishnan

Clinical Trial

Prevention of Recurrence of Crohn’s Disease by Fecal Microbiota Therapy

Primary Researcher:
Alan Moss

Clinical Trial

Fecal Microbiota Transplantation and Supplementation in Refractory Ulcerative Colitis

Primary Researcher:
Jessica Crothers