The Center for Microbiome Informatics and Therapeutics joined the New England Chapter of Crohn’s and Colitis Foundation for their annual spin4 crohn’s and colitis cures fundraiser
A new study from an MIT-led team has revealed that these bacterial populations can remake themselves within the lifetime of their host, by passing genes back and forth.
To better understand the pathologic impact of intestinal bile acids on host health, CMIT faculty designed a non-toxic inhibitor that reduces secondary bile acid production in the intestine to better understand the impact of these metabolites.
Researchers create a novel computer model that predicts the metabolic activity of new microbial communities using widely available metagenomic sequencing.
A common intestinal commensal bacteria induces T cell-dependent immunoglobulin production during periods of homeostasis, uncovering a novel pathway through which the microbiome may contribute to immune dysregulation and Inflammatory Bowel Disease.
In a recently published paper in Nature, CMIT faculty provide a comprehensive review of the scientific advances that have brought us to our current understanding of Inflammatory Bowel Disease (IBD) pathophysiology.
Researchers identify a specific lipid metabolite that is abnormally abundant in IBD patients. Their subsequent investigations reveal how this metabolite stimulates the growth of species that are well established to be overrepresented in IBD patients.