Predictive Metabolomic Profiling of Microbial Communities Using Amplicon or Metagenomic Sequences

Researchers create a novel computer model that predicts the metabolic activity of new microbial communities using widely available metagenomic sequencing.

Multi-omics of the Gut Microbial Ecosystem in Inflammatory Bowel Diseases

In a recently published paper in Nature, Lloyd-Price (et.al) provide a comprehensive analysis of the longitudinal variation in the gut microbiome of patients with IBD.

A Library of Human Gut Bacterial Isolates Paired with Longitudinal Multiomics Data Enables Mechanistic Microbiome Research

The Broad Institute and OpenBiome Microbiome Library (BIO-ML) now supplies a comprehensive collection of nearly 8,000 intestinal bacterial isolates, paired with nearly 4,000 genome sequences, to serve as an open access investigational resource.

Ruminococcus gnavus, a Member of the Human Gut Microbiome Associated with Crohn’s Disease, Produces an Inflammatory Polysaccharide

By Katie E. Golden The microbial communities that live peacefully in our gut play a critical role in healthy metabolism and immunity. Evolving research on the microbiome has linked chronic disease, like Inflammatory Bowel Disease (IBD), to significant and characteristic disruptions in both the types and relative abundance of bacterial species that colonize the intestine. […]

Getting to Know Hera Vlamakis, PhD

By Katie E. Golden, MD I recently had the opportunity to talk with Dr. Hera Vlamakis, who is the Senior Group Leader of the Infectious Disease and Microbiome Program at the Broad Institute of MIT and Harvard. With a background in microbiology, she is interested in how the bacteria that colonize the human intestine interact […]