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CMIT Global Diversity Resource Program
The Center for Microbiome Informatics and Therapeutics (CMIT) is pleased to partner with MIT spin-out OpenBiome to provide MIT researchers with no-cost, priority access to the Global Microbiome Conservancy strain collection through a targeted pilot program.
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CMIT participates in Crohn’s and Colitis Foundation community-based fundraiser
The Center for Microbiome Informatics and Therapeutics joined the New England Chapter of Crohn’s and Colitis Foundation for their annual spin4 crohn’s and colitis cures fundraiser
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How industrialized life remodels the microbiome
A new study from an MIT-led team has revealed that these bacterial populations can remake themselves within the lifetime of their host, by passing genes back and forth.
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Development of a Covalent Inhibitor of Gut Bacterial Bile Salt Hydrolases
To better understand the pathologic impact of intestinal bile acids on host health, CMIT faculty designed a non-toxic inhibitor that reduces secondary bile acid production in the intestine to better understand the impact of these metabolites.
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Gut Microbiota Composition and Functional Changes in Inflammatory Bowel Disease and Irritable Bowel Syndrome
Authors unveil a large-scale metagenomic microbiome analysis from patients with both Inflammatory Bowel Disease and Irritable Bowel Syndrome.
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Predictive Metabolomic Profiling of Microbial Communities Using Amplicon or Metagenomic Sequences
Researchers create a novel computer model that predicts the metabolic activity of new microbial communities using widely available metagenomic sequencing.
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Functional Heterogeneity in the Fermentation Capabilities of the Healthy Human Gut Microbiota
A new study by Gurry and fellow CMIT colleagues explores the relationship between fiber intake and microbial Short Chain Fatty Acid production
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Synthetic Gene Circuits Enable Systems-Level Biosensor Trigger Discovery at the Host-Microbe Interface
Engineered microbes with condition-responsive circuits can be used to record physiological and environmental conditions as they pass through the gut.
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Akkermansia Muciniphila Induces Intestinal Adaptive Immune Responses during Homeostasis
A common intestinal commensal bacteria induces T cell-dependent immunoglobulin production during periods of homeostasis, uncovering a novel pathway through which the microbiome may contribute to immune dysregulation and Inflammatory Bowel Disease.
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Pathway Paradigms Revealed from the Genetics of Inflammatory Bowel Disease
In a recently published paper in Nature, CMIT faculty provide a comprehensive review of the scientific advances that have brought us to our current understanding of Inflammatory Bowel Disease (IBD) pathophysiology.