Unraveling the processes shaping mammalian gut microbiomes over evolutionary time.

Groussin, M. et al., Nat Commun. 2017 Feb 23;8:14319. doi: 10.1038/ncomms14319 Whether mammal-microbiome interactions are persistent and specific over evolutionary time is controversial. Here we show that host phylogeny and major dietary shifts have affected the distribution of different gut bacterial lineages and did so on vastly different bacterial phylogenetic resolutions. Diet mostly influences the acquisition of […]

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Two dynamic regimes in the human gut microbiome.

Gibbons, S.M.., et al., PLoS Comput Biol. 2017 Feb 21;13(2):e1005364. doi: 10.1371/journal.pcbi.1005364 The gut microbiome is a dynamic system that changes with host development, health, behavior, diet, and microbe-microbe interactions. Prior work on gut microbial time series has largely focused on autoregressive models (e.g. Lotka-Volterra). However, we show that most of the variance in microbial time series […]

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