Ectopic colonization of oral bacteria in the intestine drives TH1 cell induction and inflammation.

Atarashi K et al. Science. 2017 Oct 20;358(6361):359-365. Intestinal colonization by bacteria of oral origin has been correlated with several negative health outcomes, including inflammatory bowel disease. However, a causal role of oral bacteria ectopically colonizing the intestine remains unclear. Using gnotobiotic techniques, we show that strains of Klebsiellaspp. isolated from the salivary microbiota are strong inducers […]

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